Interactive Karyotype Activity Info

Bell Ringer (5 min): Show a photo of a human karyotype. Ask: "What is different about the last pair (Pair 23) in a male vs. a female?"

Direct Instruction (10 min): Explain nondisjunction (chromosomes failing to separate). Do not lecture on every disorder; just explain how the error happens. Interactive Karyotype Activity

The Activity (25 min): Students complete one "Normal" patient and one "Abnormal" patient. Bell Ringer (5 min): Show a photo of a human karyotype

Closure (10 min): "If you were a genetic counselor and saw an extra chromosome on pair #18, what would you tell the parents?" (Answer: Edwards syndrome). Closure (10 min): "If you were a genetic

Once all 46 chromosomes are arranged in 23 pairs, the software automatically scans for numerical abnormalities.

The screen displays a chaotic "cell in metaphase." Chromosomes are scattered randomly across the screen, often overlapping and rotated. Students are instructed to "capture" the image.