In Resident Evil 4, you save only at typewriters using ink ribbons.
If you have no ink ribbons, you cannot save. Ink ribbons are finite but plentiful. Save Data Resident Evil 4 Aether Sx2
Search for "PCSX2 Memory Card Save Resident Evil 4" (do not search for "AetherSX2" specifically, as it uses the same format as PCSX2). In Resident Evil 4 , you save only
Save data refers to the small files that record your in-game progress, inventory, and game state. On the original PS2, these were stored on memory cards. AetherSX2 emulates that behavior by using virtual memory card files (commonly with a .ps2 or .psu-like structure inside the emulator’s virtual MC folder) or by mapping saves to exported files that mimic the PS2 memory card format. Proper handling ensures your game progress persists across app updates, device changes, or ROM moves. If you have no ink ribbons, you cannot save
If you only have a Save State but no memory card save:
Use FolderSync or Syncthing to automatically sync your /memcards/ folder to Google Drive. This way, if you uninstall AetherSX2, your save isn't lost.